c. 1400, from Late Latin exacerbationem (nominative exacerbatio), noun of action from past participle stem of Latin exacerbare "exasperate, irritate, provoke," from ex- "thoroughly" (see ex-) + acerbus "harsh, bitter," from acer "sharp, keen" (see acrid).
1. Bleeding may be herralded by several day of exacerbation of pain.
2. For several days, he has had an exacerbation of ulcer symptoms.
3. Nonetheless, none of these pathogens is associated with severity of asthma exacerbation.
4. His foolishness was followed by an exacerbation of their quarrel.
5. Eczema exacerbation, Jishi fish, shrimp, seafood and other foods prone to allergies.