early 15c., from Middle French dépendance, from dependre (see depend). Originally also dependance (the earlier form), depending whether the writer had French or Latin foremost in mind; the Latin form gradually predominated and after c. 1800 dependance is rare. As an adjective from c. 1600.
1. his dependence on his parents
2. Many sufferers have been reclaimed from a dependence on alcohol.
3. He was freed from financial dependence on his parents.
4. Doctors keep trying to break her dependence of the drug.
5. He lived in a state of dependence on his friend's help.