mid-13c., amis "off the mark," also "out of order," literally "on the miss," from a "in, on" (see a- (1)) + missen "fail to hit" (see miss (v.)). To take (something) amiss originally (late 14c.) was "to miss the meaning of" (see mistake). Now it means "to misinterpret in a bad sense."
1. A bit of charm and humour would not go amiss.
2. Something is radically amiss in our health care system.
3. Their instincts warned them something was amiss.
4. She sensed something was amiss and called the police.
5. His joke was taken amiss by some of the company.