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regretful (adj.)
1640s, "full of regret," from
regret
+
-ful
.
Regretfully
, properly "with regret," incorrectly used in place of
regrettably
"it is to be regretted that; calling for regret" since at least 1965. "A regrettable use, prob. after HOPEFULLY
adv.2
" [OED].