Bisphosphonate have bone? Seeking affinity, some of them are used as drugs for osteoporosis.
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2. 目的设计并合成苯并吡喃酮酯衍生物并探索其趋骨性。
OBJECTIVE to design and synthesize benzopyrone ester derivatives and to test their bone affinity.
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3. 结论部分设计的苯并吡喃4酮衍生物具有比四环素更好的趋骨性。
Conclusion Some of the benzopyran-4-one derivatives synthesized have better bone affinities compared with tetracycline.
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4. 目的根据具有趋骨性的化合物的共同特征，设计并合成苯并吡喃4酮类化合物，检测它们的趋骨性。
Aim to design and synthesize benzopyran-4-one derivatives according to the common structural properties of compounds which have bone affinity and test their bone affinity.
Conclusion Bone-targeting drugs and carriers with low toxicity, high stability and strong bone affinity are valuable to be exploited and applied.
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6. 目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE To study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation.
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7. 目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE to study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation. METHODS Inhibitory zone diameter was measured by disc AGAR diffusion (DAD).
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8. 目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE to study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation. METHODS Inhibitory zone diameter was measured by disc AGAR diffusion (DAD).
