1. 目的:建立替莫唑酯中有关物质的测定方法。
Objective: to develop a method so as to determine the related substances in the temozolomide hexyl ester.

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2. 替莫唑的疗效复发胶质母细胞瘤多是有限的。
Efficacy of temozolomide in recurrent glioblastoma multiforme is limited.

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3. 最好考虑年轻患者治疗原发性胶质母细胞瘤多谁状况良好伴和辅助替莫唑胺
It is advisable to consider treating young patients with primary glioblastoma multiforme who are in good condition with concomitant and adjuvant temozolomide.

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4. 目的通过对比观察脑恶性胶质瘤术后替莫唑胺胶囊联合外放射治疗的疗效及安全性。
Objective To compare the curative effects and safety of temozolomide plus radiotherapy in the treatment of post-operative malignant glioma.

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5. 有新的科学数据,有关治疗性胶质母细胞瘤伴多替和辅助手术后及放射治疗。
There are new scientific data concerning the treatment of patients with glioblastoma multiforme with concomitant and adjuvant temozolomide following surgery and radiotherapy.

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6. 2005年,一种叫替(抗肿瘤药物)的新药能使脑癌患者的生命延长几个月。
In two thousand five, a drug called temozolomide was shown to add a few months to the lives of brain cancer patients.

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7. 对于复发的病人,替对间变胶质瘤是有效的。作为辅助治疗,它和PC V方案有同等的效果。
At recurrence temozolomide is effective for anaplastic tumors; well-tolerated and probably equally effective is PCV used as adjuvant therapy.

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8. 术后替化疗组中位无进展生存期较单纯手术组显著延长(P其余各组之间差异无统计学意义。
PFS of temozolomide chemotherapy group is higher than that of single operation group(Pno significant differences of PFS between the other groups.

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9. 术后替化疗组中位无进展生存期较单纯手术组显著延长(P其余各组之间差异无统计学意义。
PFS of temozolomide chemotherapy group is higher than that of single operation group(Pno significant differences of PFS between the other groups.

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