The objective is to synthesize 5-fluorouracil derivatives containing 2-5 carbon alkanoic acid.
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2. 目的制备氟尿嘧啶壳聚糖微球。
OBJECTIVE To investigate the preparation of fluorouracil loaded chitosan microspheres.
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3. 卡培他滨和氟尿嘧啶的毒副作用相似。
Toxic effects of capecitabine and fluorouracil were similar.
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4. 目的:研究氟尿嘧啶乙酸口服给药后的药代动力学。
Objective: To study the pharmacokinetics of fluorouracil acetic acid (FUAC) after oral administration.
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5. 顺铂联合氟尿嘧啶仍是晚期食管痛的基本治疗方案;
Cisplatin in combination with fluorouracil still is considered as the basic therapeutic scheme for advanced esophageal cancer.
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6. 目的考察氟尿嘧啶注射液与8种常用输液配伍的稳定性。
Objective To study the stability of fluorouracil injection in 8 different conventional infusion fluids.
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7. 点击阅读共计81页报告全文:氟尿嘧啶事件根源分析。
Click here to read the full 81 page report: Fluorouracil Incident Root Cause Analysis (PDF reader required).
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8. 结论:氟尿嘧啶微球体外释药以药物扩散和材料降解为主。
Conclusion: The fluorouracil release from microspheres with polylactic acid as carriers was controlled by drug diffusion and polymeric erosion.
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9. 目的合成含2~5个碳的直链烷酸功能基的5-氟尿嘧啶衍生物。
Objective To synthesize 5-fluorouracil derivatives containing 2-5 carbon alkanoic acid.
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10. 目的研究环磷酰胺和5氟尿嘧啶对卵巢透明细胞腺癌的协同作用。
Objective To investigate the synergistic action of cyclophosphamide and 5 fluorouracil in ovarian clear cell adenocarcinoma.
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11. 结论方法简便,准确,可作为植入用缓释氟尿嘧啶的质量控制方法。
CONCLUSION This method is simple, accurate and suitable for the quality control of fluorouracil sustained-release for implant.
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12. 方法以聚乳酸为载体材料,OW型乳化挥发法制备氟尿嘧啶微球;
METHODS An O/W emulsion-solvent evaporation method was used to prepare fluorouracil sustained release microspheres.
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13. 达到50%以上抑制率的药物只有丝裂霉素、5氟尿嘧啶、阿霉素。
The chemotherapeutics which inhibition rate was more than 50% were mitomycin, 5-FU, and Adriamycin.
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14. 结果表明,牛磺酸可减轻氟尿嘧啶引起的大鼠小肠结构和吸收功能障碍。
The results indicated that taurine could prevent small intestinal structure injury and reduction of tryptophan absorption in rats administrated with fluorouracil.
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15. 结论二次乳化法和冻融法结合能显著提高5-氟尿嘧啶脂质体的包封率。
Conclusion Double emulsification and freeze-thawing method can significantly increase the encapsulation efficiency 5-FU in liposomes.
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16. 目的探讨对以羧甲基壳聚糖为载体的氟尿嘧啶微球体外释药特性的影响因素。
Objective to study the release characteristics of fluorouracil-loaded carboxymethyl chitosan microspheres (Fu-CMCS-MS) in vitro.
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17. 目的探讨对以羧甲基壳聚糖为载体的氟尿嘧啶微球体外释药特性的影响因素。
Objective to prepare carboxymethyl chitosan microspheres of fluorouracil (FU-CMCS-MS), and measure the releasing of FU-CMCS-MS in vitro.
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18. 目的:探讨5 -氟尿嘧啶与转移因子联合治疗多发性跖疣的疗效和安全性。
Objective: to evaluate the clinical efficacy and safety of 5-flucytosine combined with transfer factor treating for multiple verruca plantaris.
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19. 目的研究多烯脂肪酸减轻5-氟尿嘧啶(5-FU)对免疫系统的损害程度。
PurposeTo study the degree of polyenoic fatty acids to alleviate the influence of 5-FU on immune system.
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20. 目的:观察家兔角巩膜缘局部应用5 -氟尿嘧啶(5 - FU)的治疗效果。
AIM: to observe the effects of topical application of 5-fluorouracil (5-fu) on the rabbits corneal limbus.
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21. 目的评价氟尿嘧啶动物胃左动脉灌注和外周静脉化疗药物动力学的基础实验比较。
Objective To compare the pharmacokinetics on rabbit after left gastric regional arterial infusion chemotherapy with peripheral intravenous administration.
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22. 目的研究旋转恒定磁场对5-氟尿嘧啶(5-FU)损伤小鼠造血功能的保护作用。
ObjectiveTo study the hemoprotective effects of rotating and stationary magnetic field(RSMF) in mice treated with 5-Fluorouracil(5-FU).
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23. 氟尿嘧啶植入剂可提高局部药物浓度,延长有效药物浓度时间,降低全身毒副反用。
Fluorouracil for implantation can elevate the local drug concentration, extend the time of effective drug concentration, reduce the general toxic and side-effect.
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24. 接下四个月的化疗(5 -氟尿嘧啶持续滴注)回到匹兹堡做,直到2007年5月。
The next four months of chemo (continuous infusion 5-fu) was back in Pittsburgh, through May 2007.
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25. 目的比较两种化疗泵配合PICC在5-氟尿嘧啶持续泵入化疗中应用的效果。
Objective To compare the effects of two chemotherapy pumps combined with PICC in 5-FU continuous pump infusion.
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26. 采用五种不同方法制备5-氟尿嘧啶聚乳酸微囊,并对其外观性质及药物含量等进行了比较。
Polylactic acid microspheres containing 5-fluorouracil were prepared by five different methods, and studied with the optical microscope. The drug contents in microspheres were determined.
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27. 目的:这项研究旨在比较局部应用丝裂霉素C和5-氟尿嘧啶预防推板切除术后硬膜外粘连的效果。
The effectiveness of the topical application of mitomycin C (MMC) or 5-fluorouracil (5FU) in preventing peridural adhesion after laminectomy was compared in this study.
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28. 卡培他滨是一种新型口服氟尿嘧啶类药物,目前广泛用于乳腺癌、胃肠道肿瘤及头颈部肿瘤的治疗。
Capecitabine is a new oral drug of Fluorouracil (FU), which is widely used in the therapy of breast, gastrointestinal, head and neck cancer.
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29. 结果:在丝裂霉素C组大鼠中无明显的粘连形成,而在5 -氟尿嘧啶及对照组中发现严重的粘连。
No obvious adhesion formed in the rats in the MMC group, but severe peridural adhesions were found in those in the 5fu and control groups.
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30. 结论:卡培他滨和奥沙利铂用于先前未经治疗的食管癌和胃癌患者,效果分别与氟尿嘧啶和顺铂相同。
Conclusions Capecitabine and oxaliplatin are as effective as fluorouracil and cisplatin, respectively, in patients with previously untreated esophagogastric cancer.