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spite: spite: [13] Spite was adapted from Old French despit ‘scorn, ill will’, which was also borrowed intact as despite [13]. This came from Latin dēspectus, the past participle of dēspicere ‘look down on’ (source of English despise [13]), which was a compound verb formed from the prefix dē- ‘down’ and specere ‘look’ (source of English spectacle, spy, etc). The use of in spite of and despite for ‘notwithstanding’ goes back via an intermediate ‘in defiance of’ to an original ‘in contempt of’.
=> despise, species, spectator, spy
despicable (adj.): 1550s, from Late Latin despicabilis, from Latin despicari "despise, disdain, look down on," from de- "down" (see de-) + spicare, variant of specere "to look" (see scope (n.1)).
despise (v.): c. 1300, from Old French despis-, present participle stem of despire "to despise," from Latin despicere "look down on, scorn," from de- "down" (see de-) + spicere/specere "look at" (see scope (n.1)). Related: Despised; despising.
look (v.): Old English locian "use the eyes for seeing, gaze, look, behold, spy," from West Germanic *lokjan (cognates: Old Saxon lokon "see, look, spy," Middle Dutch loeken "to look," Old High German luogen, German dialectal lugen "to look out"), of unknown origin, perhaps cognate with Breton lagud "eye." In Old English, usually with on; the use of at began 14c. Meaning "seek, search out" is c. 1300; meaning "to have a certain appearance" is from c. 1400. Of objects, "to face in a certain direction," late 14c.

Look after "take care of" is from late 14c., earlier "to seek" (c. 1300), "to look toward" (c. 1200). Look into "investigate" is from 1580s; look up "research in books or papers" is from 1690s. To look down upon in the figurative sense is from 1711; to look down one's nose is from 1921. To look forward "anticipate" is c. 1600; meaning "anticipate with pleasure" is mid-19c. To not look back "make no pauses" is colloquial, first attested 1893. In look sharp (1711) sharp originally was an adverb, "sharply."
nose (n.): Old English nosu, from Proto-Germanic *nusus (cognates: Old Norse nös, Old Frisian nose, Dutch neus, Old High German nasa, German Nase), from PIE *nas- "nose" (cognates: Sanskrit nasa, Old Persian naham, Old Church Slavonic nasu, Lithuanian nosis, Latin nasus "nose"). Used of any prominent or projecting part from 1530s. (nose cone in the space rocket sense is from 1949). Used to indicate "something obvious" from 1590s. Meaning "odor, scent" is from 1894.
Kiv, It could bee no other then his owne manne, that had thrust his nose so farre out of ioynte. ["Barnabe Riche His Farewell to Military Profession," 1581]
Pay through the nose (1670s) seems to suggest "bleed." Many extended meanings are from the horse-racing sense of "length of a horse's nose," as a measure of distance between two finishers (1908). To turn up one's nose "show disdain" is from 1818 (earlier hold up one's nose, 1570s); similar notion in look down one's nose (1921). To say something is under (one's) nose "in plain view" is from 1540s.
oversee (v.): Old English oferseon "to look down upon, keep watch over, survey, observe;" see over + see (v.). Meaning "to supervise" is attested from mid-15c. The verb lacks the double sense of similar overlook, but this emerges in the noun form oversight. Related: Oversaw; overseen.