Objective: To study the synthesis of levetiracetam.
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2. 左乙拉西坦组与丙戊酸钠组差异无统计学意义。
There were no significant differences between the levetiracetam and valproate groups.
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3. 本发明涉及一种左乙拉西坦缓释微丸胶囊制剂及其制备方法。
The invention relates to a levetiracetam slow release pellet capsule preparation and a preparation method thereof.
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4. 本研究系统评价左乙拉西坦治疗儿童癫癎的有效性和安全性。
This study performed a systematic review to evaluate the effectiveness and safety of levetiracetam therapy for childhood epilepsy.
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5. 本文简要介绍了左乙拉西坦和波生坦的药理作用及其合成意义。
We briefly discussed pharmacology and significance of both levetiracetam and bosentan in the paper.
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6. 目的采用高效液相色谱法手性拆分左乙拉西坦片中的右旋异构体。
Objective A practicable method for separation and quantitative analysis of REV in Levetiracetam tablets by HPLC.
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7. 结论：目前证据表明，左乙拉西坦治疗儿童癫癎有效，但仍需更多实验数据支持。
CONCLUSIONS: the current evidence shows that levetiracetam therapy is effective for childhood epilepsy.
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8. 筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo- butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
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9. 筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
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10. 左乙拉西坦是一种新型的口服抗癫痫药物，与其他抗癫痫药物的结构不同，具有全新的抗癫痫机制。
Levetiracetam (Lev) is a novel orally active antiepileptic drug, structurally unrelated to other antiepileptics and with an entirely unique preclinical profile.
Levetiracetam is an antiepileptic drug with novel antiepileptic mechanism, in which binding to SV2A, a synaptic vesicle protein, may result in its anticonvulsant activity.
Levetiracetam was prepared from L-methionine via reduction-dethiomethylation, esterification, ammonolysis, amidation and intramolecular cyclocondensation reaction with 44.6% overall yield.
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13. 大多数的左卡尼汀或氨基乙磺酸都是合成的，因为这样做价格比较便宜。
Most L-carnitine and taurine supplements are synthetic, because it's cheaper to produce them that way.
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14. 有充分的证据表明扩张型心肌病与遗传和缺乏左卡尼汀或氨基乙磺酸有关。
There is a good deal of evidence correlating dilated cardiomyopathy with both genetic factors and a deficiency in either L-carnitine or taurine.
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15. 在素食狗健康调查的结果中，扩张型心肌病是一个问题，建议在素食中补充左卡尼汀或氨基乙磺酸。
In the results of the vegetarian Dog Health Survey, the issue of dilated cardiomyopathy (DCM) was raised and it was suggested that vegetarian diets be supplemented with L-carnitine or taurine.
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16. 在素食狗健康调查的结果中，扩张型心肌病是一个问题，建议在素食中补充左卡尼汀或氨基乙磺酸。
In the results of the vegetarian Dog Health Survey, the issue of dilated cardiomyopathy (DCM) was raised and it was suggested that vegetarian diets be supplemented with L-carnitine or taurine.
